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1. For skin whitening, it inhibits tyrosinase activity and blocks melanin production, which has whitening and spot lightening effects.
2. In addition, ellagic acid can effectively protect from external damage. It blocks tyrosinase activity, inhibits melanin production, and has an antioxidant effect. That is to say, it is excellent in shutting down the reaction of melanin pigment production in melanogenic cells and has antioxidant effect.
3. Ellagic acid has strong free radical scavenging and antioxidant ability. Ellagic acid has a scavenging effect on both oxygen radicals and hydroxyl radicals, and its ability to scavenge free radicals is higher in size than antioxidants such as sesquiterpene, olive leaf extract and luteolin.
4. Ellagic acid also strongly inhibits lipid peroxidation induced by adriamycin. Ellagic acid inhibits iron myoglobin / hydrogen peroxide-dependent lipid peroxidation. Ellagic acid prevents lipid peroxidation (LPO) triggered by exogenous substances in T cells, inhibits reactive oxygen species (ROS) production, and ameliorates cell death caused by cytotoxins.
5. Ellagic acid is a potent inhibitor of eosinophils and can be used to treat allergic inflammation. Ellagic acid has hepatoprotective effects as it is resistant to carbon tetrachloride-induced hepatotoxicity in vivo and in vitro, and also resists tert-butyl hydroperoxide-induced lipid peroxidation.
1. Antibacterial and enhance the role of immune function: tests have shown that honeysuckle has an inhibitory effect on S. typhi, S. paratyphi, E. coli, S. pyogenes, P. aeruginosa, S. pertussis, Vibrio cholerae, Staphylococcus, Streptococcus, Diplococcus pneumoniae, Meningococcus, etc.
2. Inhibition of drug-resistant bacteria protein synthesis: honeysuckle extract has a significant stimulating effect on the respiration of drug-resistant strains of Staphylococcus aureus, mostly used for medical and surgical inflammation caused by drug-resistant strains, such as the treatment of tuberculosis complicating respiratory tract infections, pneumonia, acute bacterial dysentery, diarrhea. It is also used to reduce the rate of pharyngeal carriage.
3. Anti-allergic
Lonicera japonica aqueous extract has been tested by hyaluronidase in vitro inhibition test and its inhibition rate of hyaluronic acid reached 69.54%, which has good anti-allergic property and is suitable for use in anti-allergic cosmetics. Moreover, the hemolysis rate of Lonicera japonica extract in red blood cell hemolysis test is less than 20%, which indicates that it is less irritating to human skin and can be used in cosmetics to reduce the irritation of chemical preservatives to the skin.
1. For skin whitening, it inhibits tyrosinase activity and blocks melanin production, which has whitening and spot lightening effects.
2. In addition, ellagic acid can effectively protect from external damage. It blocks tyrosinase activity, inhibits melanin production, and has an antioxidant effect. That is to say, it is excellent in shutting down the reaction of melanin pigment production in melanogenic cells and has antioxidant effect.
3. Ellagic acid has strong free radical scavenging and antioxidant ability. Ellagic acid has a scavenging effect on both oxygen radicals and hydroxyl radicals, and its ability to scavenge free radicals is higher in size than antioxidants such as sesquiterpene, olive leaf extract and luteolin.
4. Ellagic acid also strongly inhibits lipid peroxidation induced by adriamycin. Ellagic acid inhibits iron myoglobin / hydrogen peroxide-dependent lipid peroxidation. Ellagic acid prevents lipid peroxidation (LPO) triggered by exogenous substances in T cells, inhibits reactive oxygen species (ROS) production, and ameliorates cell death caused by cytotoxins.
5. Ellagic acid is a potent inhibitor of eosinophils and can be used to treat allergic inflammation. Ellagic acid has hepatoprotective effects as it is resistant to carbon tetrachloride-induced hepatotoxicity in vivo and in vitro, and also resists tert-butyl hydroperoxide-induced lipid peroxidation.
1. Antibacterial and enhance the role of immune function: tests have shown that honeysuckle has an inhibitory effect on S. typhi, S. paratyphi, E. coli, S. pyogenes, P. aeruginosa, S. pertussis, Vibrio cholerae, Staphylococcus, Streptococcus, Diplococcus pneumoniae, Meningococcus, etc.
2. Inhibition of drug-resistant bacteria protein synthesis: honeysuckle extract has a significant stimulating effect on the respiration of drug-resistant strains of Staphylococcus aureus, mostly used for medical and surgical inflammation caused by drug-resistant strains, such as the treatment of tuberculosis complicating respiratory tract infections, pneumonia, acute bacterial dysentery, diarrhea. It is also used to reduce the rate of pharyngeal carriage.
3. Anti-allergic
Lonicera japonica aqueous extract has been tested by hyaluronidase in vitro inhibition test and its inhibition rate of hyaluronic acid reached 69.54%, which has good anti-allergic property and is suitable for use in anti-allergic cosmetics. Moreover, the hemolysis rate of Lonicera japonica extract in red blood cell hemolysis test is less than 20%, which indicates that it is less irritating to human skin and can be used in cosmetics to reduce the irritation of chemical preservatives to the skin.
Items | Specifications | Test Methods |
Identification | Positive | TLC |
Appearance & Color | Fine brown yellow powder | Visual |
Odor & Taste | Characteristic | Organoleptic |
Mesh Size | NLT 90% through 80 mesh | 80 Mesh Screen |
Moisture Content | NMT 5.0% | 5g / 105℃ / 2hrs |
Ash Content | NMT 5.0% | 2g / 525℃ / 3hrs |
Heavy Metals | NMT 10ppm | Atomic Absorption |
Arsenic (As) | NMT 1ppm | Atomic Absorption |
Cadmium (Cd) | NMT 1ppm | Atomic Absorption |
Mercury (Hg) | NMT 0.1ppm | Atomic Absorption |
Lead (Pb) | NMT 3ppm | Atomic Absorption |
Extract Solvent | Grain alcohol/Water | / |
Total Plate Count | NMT 10,000cfu/g | |
Total Yeast & Mold | NMT 1,000cfu/g | |
E. Coli | Negative | |
Salmonella | Negative | |
Staphylococcus | Negative | |
Aflatoxins | 0.2ppb |
Items | Specifications | Test Methods |
Identification | Positive | TLC |
Appearance & Color | Fine brown yellow powder | Visual |
Odor & Taste | Characteristic | Organoleptic |
Mesh Size | NLT 90% through 80 mesh | 80 Mesh Screen |
Moisture Content | NMT 5.0% | 5g / 105℃ / 2hrs |
Ash Content | NMT 5.0% | 2g / 525℃ / 3hrs |
Heavy Metals | NMT 10ppm | Atomic Absorption |
Arsenic (As) | NMT 1ppm | Atomic Absorption |
Cadmium (Cd) | NMT 1ppm | Atomic Absorption |
Mercury (Hg) | NMT 0.1ppm | Atomic Absorption |
Lead (Pb) | NMT 3ppm | Atomic Absorption |
Extract Solvent | Grain alcohol/Water | / |
Total Plate Count | NMT 10,000cfu/g | |
Total Yeast & Mold | NMT 1,000cfu/g | |
E. Coli | Negative | |
Salmonella | Negative | |
Staphylococcus | Negative | |
Aflatoxins | 0.2ppb |